Design Principles for Broad-Spectrum Protein-Crystal Nucleants with Nanoscale Pits
نویسندگان
چکیده
منابع مشابه
Design principles for broad-spectrum protein-crystal nucleants with nanoscale pits.
Growing high-quality crystals is a bottleneck in the determination of protein structures by x-ray diffraction. Experiments find that materials with a disordered pitted surface seed the growth of protein crystals. Here we report computer simulations of rapid crystal nucleation in nanoscale pits. Nucleation is rapid, as the crystal forms in pits that have filled with liquid via capillary condensa...
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ژورنال
عنوان ژورنال: Physical Review Letters
سال: 2010
ISSN: 0031-9007,1079-7114
DOI: 10.1103/physrevlett.105.205501